Purinergic P2X3 Receptors

A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.

Also Known As:

Receptors, Purinergic P2X3; P2X3 Purinoceptor; P2X3 Receptor; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3; P2X3 Receptors, Purinergic; Purinoceptor, P2X3; Receptor, P2X3

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Ligand-Gated Ion Channels: 224
        Purinergic P2X Receptors: 63
        Purinergic P2X3 Receptors: 216
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Ion Channels: 6936
        Ligand-Gated Ion Channels: 224
        Purinergic P2X Receptors: 63
        Purinergic P2X3 Receptors: 216
    - Cell Surface Receptors: 2156
      - G-Protein-Coupled Receptors: 4858
        Purinergic Receptors: 1038
        Purinergic P2 Receptors: 293
        Purinergic P2X Receptors: 63
        Purinergic P2X3 Receptors: 216
      - Neurotransmitter Receptors: 577
        Purinergic Receptors: 1038
        Purinergic P2 Receptors: 293
        Purinergic P2X Receptors: 63
        Purinergic P2X3 Receptors: 216
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Ligand-Gated Ion Channels: 224
        Purinergic P2X Receptors: 63
        Purinergic P2X3 Receptors: 216

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Disease

Drug/Important Bio-Agent (IBA)